SDH mutations in cancer

The SDHA, SDHB, SDHC, SDHD genes encode the four subunits of succinate dehydrogenase (SDH; mitochondrial complex II), a mitochondrial enzyme involved in two essential energy-producing metabolic processes of the cell, the Krebs cycle and the electron transport chain. Germline loss-of-function mutatio...

Повний опис

Бібліографічні деталі
Автори: Bardella, C, Pollard, P, Tomlinson, I
Формат: Journal article
Мова:English
Опубліковано: 2011