Novel approaches to control malaria in forested areas of Southeast Asia

The emergence and spread of drug resistance in the Greater Mekong Subregion (GMS) have added urgency to accelerate malaria elimination while reducing the treatment options. The remaining foci of malaria transmission are often in forests, where vectors tend to bite during daytime and outdoors, thus r...

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প্রধান লেখক: Von Seidlein, L, Peto, T, Tripura, R, Pell, C, Yeung, S, Kindermans, J, Dondorp, A, Maude, R
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Elsevier 2019
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author Von Seidlein, L
Peto, T
Tripura, R
Pell, C
Yeung, S
Kindermans, J
Dondorp, A
Maude, R
author_facet Von Seidlein, L
Peto, T
Tripura, R
Pell, C
Yeung, S
Kindermans, J
Dondorp, A
Maude, R
author_sort Von Seidlein, L
collection OXFORD
description The emergence and spread of drug resistance in the Greater Mekong Subregion (GMS) have added urgency to accelerate malaria elimination while reducing the treatment options. The remaining foci of malaria transmission are often in forests, where vectors tend to bite during daytime and outdoors, thus reducing the effectiveness of insecticide-treated bed nets. Limited periods of exposure suggest that chemoprophylaxis could be a promising strategy to protect forest workers against malaria. Here we discuss three major questions in optimizing malaria chemoprophylaxis for forest workers: which antimalarial drug regimens are most appropriate, how frequently the chemoprophylaxis should be delivered, and how to motivate forest workers to use, and adhere to, malaria prophylaxis.
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spelling oxford-uuid:7f4c9cd6-934f-4abe-a29b-376b501d058f2022-03-26T21:16:07ZNovel approaches to control malaria in forested areas of Southeast AsiaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7f4c9cd6-934f-4abe-a29b-376b501d058fEnglishSymplectic Elements at OxfordElsevier2019Von Seidlein, LPeto, TTripura, RPell, CYeung, SKindermans, JDondorp, AMaude, RThe emergence and spread of drug resistance in the Greater Mekong Subregion (GMS) have added urgency to accelerate malaria elimination while reducing the treatment options. The remaining foci of malaria transmission are often in forests, where vectors tend to bite during daytime and outdoors, thus reducing the effectiveness of insecticide-treated bed nets. Limited periods of exposure suggest that chemoprophylaxis could be a promising strategy to protect forest workers against malaria. Here we discuss three major questions in optimizing malaria chemoprophylaxis for forest workers: which antimalarial drug regimens are most appropriate, how frequently the chemoprophylaxis should be delivered, and how to motivate forest workers to use, and adhere to, malaria prophylaxis.
spellingShingle Von Seidlein, L
Peto, T
Tripura, R
Pell, C
Yeung, S
Kindermans, J
Dondorp, A
Maude, R
Novel approaches to control malaria in forested areas of Southeast Asia
title Novel approaches to control malaria in forested areas of Southeast Asia
title_full Novel approaches to control malaria in forested areas of Southeast Asia
title_fullStr Novel approaches to control malaria in forested areas of Southeast Asia
title_full_unstemmed Novel approaches to control malaria in forested areas of Southeast Asia
title_short Novel approaches to control malaria in forested areas of Southeast Asia
title_sort novel approaches to control malaria in forested areas of southeast asia
work_keys_str_mv AT vonseidleinl novelapproachestocontrolmalariainforestedareasofsoutheastasia
AT petot novelapproachestocontrolmalariainforestedareasofsoutheastasia
AT tripurar novelapproachestocontrolmalariainforestedareasofsoutheastasia
AT pellc novelapproachestocontrolmalariainforestedareasofsoutheastasia
AT yeungs novelapproachestocontrolmalariainforestedareasofsoutheastasia
AT kindermansj novelapproachestocontrolmalariainforestedareasofsoutheastasia
AT dondorpa novelapproachestocontrolmalariainforestedareasofsoutheastasia
AT mauder novelapproachestocontrolmalariainforestedareasofsoutheastasia