Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.

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The HMG-box transcription factor Sox2 plays a role throughout neurogenesis and also acts at other stages of development, as illustrated by the multiple organs affected in the anophthalmia syndrome caused by SOX2 mutations. Here we combined proteomic and genomic approaches to characterize gene regula...

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Hlavní autoři: Engelen, E, Akinci, U, Bryne, J, Hou, J, Gontan, C, Moen, M, Szumska, D, Kockx, C, van Ijcken, W, Dekkers, D, Demmers, J, Rijkers, E, Bhattacharya, S, Philipsen, S, Pevny, L, Grosveld, F, Rottier, R, Lenhard, B, Poot, R
Médium: Journal article
Jazyk:English
Vydáno: 2011

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