Nucleoporin 54 contributes to Homologous recombination repair and post-replicative DNA integrity
The nuclear pore complex (NPC) machinery is emerging as an important determinant in the maintenance of genome integrity and sensitivity to DNA double-strand break (DSB)-inducing agents, such as ionising radiation (IR). In this study, using a high-throughput siRNA screen, we identified the central ch...
المؤلفون الرئيسيون: | Rodriguez-Berriguete, G, Granata, G, Puliyadi, R, Tiwana, G, Prevo, R, Wilson, R, Yu, S, Buffa, F, Humphrey, T, McKenna, W, Higgins, G |
---|---|
التنسيق: | Journal article |
منشور في: |
Oxford University Press
2018
|
مواد مشابهة
-
Targeting TOPK 1 sensitises tumour cells to radiation-induced damage by enhancing replication stress
حسب: Herbert, K, وآخرون
منشور في: (2020) -
The anti-malarial drug atovaquone potentiates platinum-mediated cancer cell death by increasing oxidative stress
حسب: Coates, JTT, وآخرون
منشور في: (2020) -
Depletion of Signal Recognition Particle 72kDa increases radiosensitivity
حسب: Prevo, R, وآخرون
منشور في: (2017) -
CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner
حسب: Prevo, R, وآخرون
منشور في: (2018) -
Homologous recombination repair rathway and RAD54L in early-stage lung adenocarcinoma
حسب: Shaopeng Zheng, وآخرون
منشور في: (2021-02-01)