Nucleoporin 54 contributes to Homologous recombination repair and post-replicative DNA integrity
The nuclear pore complex (NPC) machinery is emerging as an important determinant in the maintenance of genome integrity and sensitivity to DNA double-strand break (DSB)-inducing agents, such as ionising radiation (IR). In this study, using a high-throughput siRNA screen, we identified the central ch...
Main Authors: | Rodriguez-Berriguete, G, Granata, G, Puliyadi, R, Tiwana, G, Prevo, R, Wilson, R, Yu, S, Buffa, F, Humphrey, T, McKenna, W, Higgins, G |
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格式: | Journal article |
出版: |
Oxford University Press
2018
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