Dose and time relationships for tumor induction in the liver and esophagus of 4080 inbred rats by chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine.
A Weibull analysis is presented of the dose and time relationships for the effects on 4080 inbred rats of chronic ingestion in the drinking water of 16 different doses of N-nitrosodimethylamine (NDMA) or N-nitrosodiethylamine (NDEA). The sites chiefly affected were the liver (by both agents) and the...
Main Authors: | Peto, R, Gray, R, Brantom, P, Grasso, P |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1991
|
Similar Items
-
Effects on 4080 rats of chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine: a detailed dose-response study.
by: Peto, R, et al.
Published: (1991) -
EFFECTS ON 4080 RATS OF CHRONIC INGESTION OF N-NITROSODIETHYLAMINE OR N-NITROSODIMETHYLAMINE - A DETAILED DOSE-RESPONSE STUDY - FUNDAMENTAL CARCINOGENIC PROCESSES AND THEIR IMPLICATIONS FOR LOW-DOSE RISK ASSESSMENT - REPLY
by: Peto, R, et al.
Published: (1993) -
Chronic nitrosamine ingestion in 1040 rodents: the effect of the choice of nitrosamine, the species studied, and the age of starting exposure.
by: Gray, R, et al.
Published: (1991) -
The Effect of N-Nitrosodimethylamine on Enzyme Activities and Histology in the Mouse
by: Salleh, Mohd Nazil
Published: (1999) -
The effect of N-nitrosodiethylamine and N-nitrosopyrolidine on gamma glutamyltranspeptidase (GGT) and alkaline phosphatase (ALP) in white mice liver
by: Ramli, Johari, et al.
Published: (1999)