Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
Scalable, integrative methods to understand mechanisms that link genetic variants with phenotypes are needed. Here we derive a mathematical expression to compute PrediXcan (a gene mapping approach) results using summary data (S-PrediXcan) and show its accuracy and general robustness to misspecified...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Springer Nature
2018
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