Intercalation and controlled release properties of vitamin C intercalated layered double hydroxide
Two drug-inorganic composites involving vitamin C (VC) intercalated in Mg-Al and Mg-Fe layered double hydroxides (LDHs) have been synthesized by the calcination-rehydration (reconstruction) method. Powder X-ray diffraction (XRD), Fourier transform infrared (FTIR), and UV-vis absorption spectroscopy...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
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2013
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| _version_ | 1797078286130479104 |
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| author | Gao, X Lei, L O'Hare, D Xie, J Gao, P Chang, T |
| author_facet | Gao, X Lei, L O'Hare, D Xie, J Gao, P Chang, T |
| author_sort | Gao, X |
| collection | OXFORD |
| description | Two drug-inorganic composites involving vitamin C (VC) intercalated in Mg-Al and Mg-Fe layered double hydroxides (LDHs) have been synthesized by the calcination-rehydration (reconstruction) method. Powder X-ray diffraction (XRD), Fourier transform infrared (FTIR), and UV-vis absorption spectroscopy indicate a successful intercalation of VC into the interlayer galleries of the LDH host. Studies of VC release from the LDHs in deionised water and in aqueous CO 32- solutions imply that Mg3Al-VC LDH is a better controlled release system than Mg3Fe-VC LDH. Analysis of the release profiles using a number of kinetic models suggests a solution-dependent release mechanism, and a diffusion-controlled deintercalation mechanism in deionised water, but an ion exchange process in CO32- solution. © 2013 Elsevier Inc. All rights reserved. |
| first_indexed | 2024-03-07T00:29:56Z |
| format | Journal article |
| id | oxford-uuid:7f6b1062-3ee5-4442-ab17-abb2c1ba5cfd |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:29:56Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:7f6b1062-3ee5-4442-ab17-abb2c1ba5cfd2022-03-26T21:16:48ZIntercalation and controlled release properties of vitamin C intercalated layered double hydroxideJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:7f6b1062-3ee5-4442-ab17-abb2c1ba5cfdEnglishSymplectic Elements at Oxford2013Gao, XLei, LO'Hare, DXie, JGao, PChang, TTwo drug-inorganic composites involving vitamin C (VC) intercalated in Mg-Al and Mg-Fe layered double hydroxides (LDHs) have been synthesized by the calcination-rehydration (reconstruction) method. Powder X-ray diffraction (XRD), Fourier transform infrared (FTIR), and UV-vis absorption spectroscopy indicate a successful intercalation of VC into the interlayer galleries of the LDH host. Studies of VC release from the LDHs in deionised water and in aqueous CO 32- solutions imply that Mg3Al-VC LDH is a better controlled release system than Mg3Fe-VC LDH. Analysis of the release profiles using a number of kinetic models suggests a solution-dependent release mechanism, and a diffusion-controlled deintercalation mechanism in deionised water, but an ion exchange process in CO32- solution. © 2013 Elsevier Inc. All rights reserved. |
| spellingShingle | Gao, X Lei, L O'Hare, D Xie, J Gao, P Chang, T Intercalation and controlled release properties of vitamin C intercalated layered double hydroxide |
| title | Intercalation and controlled release properties of vitamin C intercalated layered double hydroxide |
| title_full | Intercalation and controlled release properties of vitamin C intercalated layered double hydroxide |
| title_fullStr | Intercalation and controlled release properties of vitamin C intercalated layered double hydroxide |
| title_full_unstemmed | Intercalation and controlled release properties of vitamin C intercalated layered double hydroxide |
| title_short | Intercalation and controlled release properties of vitamin C intercalated layered double hydroxide |
| title_sort | intercalation and controlled release properties of vitamin c intercalated layered double hydroxide |
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