Protein kinase C and NF-κB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection.

Protein kinase C and NF-κB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection.

Upon activation, CD4(+) T cells release cytokines, chemokines, and other soluble factors that influence the kinetics of HIV-1 replication in macrophages (M). In this article, we show that activation of human primary T cells suppresses the early stages of HIV-1 replication in human primary Mφ by down...

Descripció completa

Dades bibliogràfiques
Autors principals:	Raposo, R, Trudgian, D, Thomas, B, Van Wilgenburg, B, Cowley, S, James, W
Format:	Journal article
Idioma:	English
Publicat:	American Association of Immunologists 2011

Ítems similars

The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4
per: van Wilgenburg, B, et al.
Publicat: (2014)

The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4
per: van Wilgenburg, B, et al.
Publicat: (2014)

Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100
per: Víctor Toledano, et al.
Publicat: (2015-01-01)

Investigation into sub-cellular CD4 distribution in human embryonic stem cell derived macrophages and its role in HIV-1 infection
per: van Wilgenburg, B
Publicat: (2012)

CD81 suppresses NF-κB signaling and is downregulated in hepatitis C virus expressing cells
per: Maximilian Bunz, et al.
Publicat: (2024-01-01)

CD38 Deficiency Downregulates the Onset and Pathogenesis of Collagen-Induced Arthritis through the NF-κB Pathway
per: Yuna Du, et al.
Publicat: (2019-01-01)

Stromal down-regulation of macrophage CD4/CCR5 expression and NF-κB activation mediates HIV-1 non-permissiveness in intestinal macrophages.
per: Ruizhong Shen, et al.
Publicat: (2011-05-01)

Lipopolysaccharide Downregulates CD163 Expression to Inhibit PRRSV Infection via TLR4-NF-κB Pathway
per: Zhenbang Zhu, et al.
Publicat: (2020-03-01)

NF-κB-inducing kinase is dispensable for activation of NF-κB in inflammatory settings but essential for lymphotoxin β receptor activation of NF-κB in primary human fibroblasts
per: Smith, C, et al.
Publicat: (2001)

NF-κB-responsive miR-155 induces functional impairment of vascular smooth muscle cells by downregulating soluble guanylyl cyclase
per: Minsik Park, et al.
Publicat: (2019-02-01)

Hepatitis C Virus Infection Induces Hepatic Expression of NF-κB-Inducing Kinase and Lipogenesis by Downregulating miR-122
per: Brianna Lowey, et al.
Publicat: (2019-08-01)

Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to mycobacteria
per: Vigerust David J, et al.
Publicat: (2009-07-01)

NF-κB Activator 1 downregulation in macrophages activates STAT3 to promote adenoma-adenocarcinoma transition and immunosuppression in colorectal cancer
per: Shunyi Wang, et al.
Publicat: (2023-03-01)

Downregulation of Macrophage-Specific Act-1 Intensifies Periodontitis and Alveolar Bone Loss Possibly via TNF/NF-κB Signaling
per: Janak L. Pathak, et al.
Publicat: (2021-03-01)

TNFα-induced macrophage chemokine secretion is more dependent on NF-κB expression than lipopolysaccharides-induced macrophage chemokine secretion
per: Ciesielski, C, et al.
Publicat: (2002)

Inhibition of Bruton's tyrosine kinase regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation
per: Purvis, GSD, et al.
Publicat: (2020)

Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
per: Wonhwa Lee, et al.
Publicat: (2020-01-01)

Hepatic NF‐κB‐Inducing Kinase and Inhibitor of NF‐κB Kinase Subunit α Promote Liver Oxidative Stress, Ferroptosis, and Liver Injury
per: Xiao Zhong, et al.
Publicat: (2021-10-01)

CD40L Priming of Platelets via NF‐κB Activation is CD40‐ and TAK1‐Dependent
per: Kevin Kojok, et al.
Publicat: (2018-12-01)

Beyond NF-κB activation: nuclear functions of IκB kinase α
per: Huang Wei-Chien, et al.
Publicat: (2013-01-01)

Fucofuroeckol-A from Eisenia bicyclis Inhibits Inflammation in Lipopolysaccharide-Induced Mouse Macrophages via Downregulation of the MAPK/NF-κB Signaling Pathway
per: Sang-Hoon Lee, et al.
Publicat: (2016-01-01)

C-phycocyanin reduces inflammation by inhibiting NF-κB activity through downregulating PDCD5 in lipopolysaccharide-induced RAW 264.7 macrophages
per: Shuai Hao, et al.
Publicat: (2018-03-01)

IκB kinase 2 but not NF-κB-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction
per: Andreakos, E, et al.
Publicat: (2003)

HIV-1 Nef impairs key functional activities in human macrophages through CD36 downregulation.
per: Eleonora Olivetta, et al.
Publicat: (2014-01-01)

Peripheral NF-κB dysregulation in people with schizophrenia drives inflammation: putative anti-inflammatory functions of NF-κB kinases
per: Caitlin E. Murphy, et al.
Publicat: (2022-01-01)

NF-κB Inducing Kinase Regulates Intestinal Immunity and Homeostasis
per: Bingran Wang, et al.
Publicat: (2022-06-01)

HIV-1 Vpu Promotes Phagocytosis of Infected CD4<sup>+</sup> T Cells by Macrophages through Downregulation of CD47
per: Lijun Cong, et al.
Publicat: (2021-08-01)

Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV.
per: Jonathan K Chan, et al.
Publicat: (2013-01-01)

MyD88 protein destabilization mitigates NF-κB-dependent protection against macrophage apoptosis
per: Duško Lainšček, et al.
Publicat: (2024-11-01)

Targeting NF-κB signaling in macrophages through drug repurposing
per: Roberti, A
Publicat: (2024)

Cover 1 - Macrophage SCAP Regulates NF-κB in NAFLD
Publicat: (2022-01-01)

NF-κB Signaling in Macrophages: Dynamics, Crosstalk, and Signal Integration
per: Michael G. Dorrington, et al.
Publicat: (2019-04-01)

Transcriptional profiling of the LPS induced NF-κB response in macrophages
per: Newham Peter, et al.
Publicat: (2007-01-01)

Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
per: Andrew Paul, et al.
Publicat: (2018-10-01)

Lipoteichoic acid obtained from Lactobacillus paracasei via low-temperature pasteurization alleviates the macrophage inflammatory response by downregulating the NF-κB signaling pathway
per: Luting Zhang, et al.
Publicat: (2023-08-01)

2-Phenylnaphthalene Derivatives Inhibit Lipopolysaccharide-Induced Pro-Inflammatory Mediators by Downregulating of MAPK/NF-κB Pathways in RAW 264.7 Macrophage Cells.
per: Chi-Fen Chang, et al.
Publicat: (2017-01-01)

AMPK-Activated Protein Kinase Suppresses Ccr2 Expression by Inhibiting the NF-κB Pathway in RAW264.7 Macrophages.
per: Fumiaki Kumase, et al.
Publicat: (2016-01-01)

Several Alphaherpesviruses Interact Similarly with the NF-κB Pathway and Suppress NF-κB-Dependent Gene Expression
per: Nicolás Romero, et al.
Publicat: (2023-08-01)

DNA-dependent protein kinase catalytic subunit binds to the transactivation domain 1 of NF-κB p65
per: Yuta Hasegawa, et al.
Publicat: (2023-09-01)

The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Activity and NF-κB p65
per: Liane Jurida, et al.
Publicat: (2015-02-01)