Safety of DNA and modified vaccinia virus Ankara vaccines against liver-stage P. falciparum malaria in non-immune volunteers.

A series of phase I clinical studies were conducted to evaluate the safety of plasmid DNA and modified vaccinia virus Ankara malaria vaccines. The vaccines each encoded a polyepitope string fused to whole Plasmodium falciparum TRAP antigen. Forty-three healthy adult volunteers received the vaccines...

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Détails bibliographiques
Auteurs principaux: Moorthy, V, McConkey, S, Roberts, M, Gothard, P, Arulanantham, N, Degano, P, Schneider, J, Hannan, C, Roy, M, Gilbert, S, Peto, T, Hill, A
Format: Journal article
Langue:English
Publié: 2003