Fluorination influences the bioisostery of myo-inositol pyrophosphate analogs

Inositol pyrophosphates (PP-IPs) are densely phosphorylated messenger molecules involved in numerous biological processes. PP-IPs contain one or two pyrophosphate group(s) attached to a phosphorylated myo-inositol ring. 5PP-IP5 is the most abundant PP-IP in human cells. To investigate the function a...

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Bibliographic Details
Main Authors: Hostachy, S, Wang, H, Zong, G, Riley, AM, Potter, BVL, Fiedler, D
Format: Journal article
Language:English
Published: Wiley 2023