Deletion of fifteen open reading frames from modified vaccinia virus Ankara fails to improve immunogenicity
Modified vaccinia virus Ankara (MVA) is a highly attenuated strain of vaccinia virus, which has been used as a recombinant vaccine vector in many vaccine development programmes. The loss of many immunosuppressive and host-range genes resulted in a safe and immunogenic vaccine vector. However it stil...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
Public Library of Science
2015
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