Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome.

Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome.

Muenke syndrome, defined by heterozygosity for a Pro250Arg substitution in fibroblast growth factor receptor 3 (FGFR3), is the most common genetic cause of craniosynostosis in humans. We have used gene targeting to introduce the Muenke syndrome mutation (equivalent to P244R) into the murine Fgfr3 ge...

Bibliografski detalji
Glavni autori:	Twigg, SR, Healy, C, Babbs, C, Sharpe, J, Wood, W, Sharpe, P, Morriss-Kay, G, Wilkie, A
Format:	Journal article
Jezik:	English
Izdano:	2009

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