Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.

Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.

BACKGROUND: Connexins are a widespread family of membrane proteins that assemble into hexameric hemichannels, also known as connexons. Connexons regulate membrane permeability in individual cells or couple between adjacent cells to form gap junctions and thereby provide a pathway for regulated inter...

Bibliográfalaš dieđut
Váldodahkkit:	Vaiyapuri, S, Jones, C, Sasikumar, P, Moraes, L, Munger, S, Wright, JR, Ali, MS, Sage, T, Kaiser, W, Tucker, K, Stain, C, Bye, A, Jones, S, Oviedo-Orta, E, Simon, A, Mahaut-Smith, M, Gibbins, J
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2012

Geahča maid

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A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury.
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Pathogenic connexin-31 forms constitutively active hemichannels to promote necrotic cell death.
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