Potential consequences for recruitment, power, and external validity of requirements for additional risk factors for eligibility in randomized controlled trials in secondary prevention of stroke.
BACKGROUND AND PURPOSE: Eligibility criteria determine the external validity (generalizability) of the results of randomized controlled trials. To increase the number of outcome events, and hence statistical power, some recent stroke prevention trials have required additional vascular risk factors...
Main Authors: | Howard, S, Algra, A, Warlow, C, Rothwell, P |
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Format: | Journal article |
Language: | English |
Published: |
2006
|
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