Synthesis of (-)-(Z)-deoxypukalide.
(Chemical Equation Presented) Closing the deal: A ring-closing metathesis (RCM)/aromatization protocol, followed by a regioselective Negishi cross-coupling reaction and macrolactonization, with subsequent RCM mediate the synthesis of (-)-(Z)-deoxypukalide in 12 linear steps and 15% overall yield (se...
Autors principals: | Donohoe, T, Ironmonger, A, Kershaw, N |
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Format: | Journal article |
Idioma: | English |
Publicat: |
2008
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