Synthesis of (-)-(Z)-deoxypukalide.
(Chemical Equation Presented) Closing the deal: A ring-closing metathesis (RCM)/aromatization protocol, followed by a regioselective Negishi cross-coupling reaction and macrolactonization, with subsequent RCM mediate the synthesis of (-)-(Z)-deoxypukalide in 12 linear steps and 15% overall yield (se...
Main Authors: | Donohoe, T, Ironmonger, A, Kershaw, N |
---|---|
Format: | Journal article |
Sprog: | English |
Udgivet: |
2008
|
Lignende værker
-
ORGN 482-Studies toward the synthesis of microsclerodermin F
af: Kershaw, J, et al.
Udgivet: (2008) -
Synthesis of (+)-DGDP and (-)-7-epialexine.
af: Donohoe, T, et al.
Udgivet: (2008) -
Application of catalytic Z-selective olefin metathesis in natural product synthesis
af: Werrel, S, et al.
Udgivet: (2015) -
Electrochemistry in tetrahydrofuran and at low temperature: protocol, procedures and methods
af: Baron, R, et al.
Udgivet: (2009) -
The effect of ortho-substitution on the efficacy of biphenyls in mediating electron transfer from lithium
af: Donohoe, T, et al.
Udgivet: (2009)