Synthesis of (-)-(Z)-deoxypukalide.

(Chemical Equation Presented) Closing the deal: A ring-closing metathesis (RCM)/aromatization protocol, followed by a regioselective Negishi cross-coupling reaction and macrolactonization, with subsequent RCM mediate the synthesis of (-)-(Z)-deoxypukalide in 12 linear steps and 15% overall yield (se...

Полное описание

Библиографические подробности
Главные авторы: Donohoe, T, Ironmonger, A, Kershaw, N
Формат: Journal article
Язык:English
Опубликовано: 2008