Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85.
Recruitment of CD2 to the immunological synapse in response to antigen is dependent on its proline-rich cytoplasmic tail. A peptide from this region (CD2:322-339) isolated CMS (human CD2AP); a related protein, CIN85; and the actin capping protein, CAPZ from a T cell line. In BIAcore analyses, the N-...
Main Authors: | Hutchings, N, Clarkson, N, Chalkley, R, Barclay, N, Brown, M |
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Format: | Journal article |
Language: | English |
Published: |
2003
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