Carbohydrate-derived amino-alcohol ligands for asymmetric alkynylation of aldehydes.

[reaction: see text] Conformationally restricted amino alcohols based on carbohydrate scaffolds provide flexible and fine-tuneable libraries that greatly expand the range of ligands available in the Zn(OTf)(2)-mediated addition of alkynes to aldehydes, in some cases with very high stereoselectivitie...

Полное описание

Библиографические подробности
Главные авторы: Emmerson, D, Hems, W, Davis, B
Формат: Journal article
Язык:English
Опубликовано: 2006
Описание
Итог:[reaction: see text] Conformationally restricted amino alcohols based on carbohydrate scaffolds provide flexible and fine-tuneable libraries that greatly expand the range of ligands available in the Zn(OTf)(2)-mediated addition of alkynes to aldehydes, in some cases with very high stereoselectivities.