The respiratory functions of blood
<p>Current views on the nature of the haemoglobin-oxygen equilibria have been reviewed and the need for improved experimental techniques stated. A multiple-addition mixing technique for investigation of the equilibria, together with the neccessary ancillary techni...
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| Format: | Thesis |
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1970
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| _version_ | 1826281656132042752 |
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| author | Seaton, B |
| author_facet | Seaton, B |
| author_sort | Seaton, B |
| collection | OXFORD |
| description | <p>Current views on the nature of the haemoglobin-oxygen equilibria have been reviewed and the need for improved experimental techniques stated. A multiple-addition mixing technique for investigation of the equilibria, together with the neccessary ancillary techniques, has been developed and an exhaustive mathematical analysis of the results, using a specially written computer programme, described. A detailed validation of the techniques has been carried out and their particular advantages and disadvantages compared with other techniques.</p> <p>The multiple-addition mixing technique has been used to investigate the effects of pH on the parameters of some of the more important models for the haemoglobin- oxygen equilibria and the results compared with those predicted from theoretical considerations.</p> <p>None of the models considered emerged as a complete description of the data obtained and guidelines for the development of new models have been given.</p> |
| first_indexed | 2024-03-07T00:32:04Z |
| format | Thesis |
| id | oxford-uuid:80264180-4287-4b15-aa53-db62c4d0a1ae |
| institution | University of Oxford |
| last_indexed | 2024-03-07T00:32:04Z |
| publishDate | 1970 |
| record_format | dspace |
| spelling | oxford-uuid:80264180-4287-4b15-aa53-db62c4d0a1ae2022-03-26T21:21:29ZThe respiratory functions of bloodThesishttp://purl.org/coar/resource_type/c_db06uuid:80264180-4287-4b15-aa53-db62c4d0a1aePolonsky Theses Digitisation Project1970Seaton, B<p>Current views on the nature of the haemoglobin-oxygen equilibria have been reviewed and the need for improved experimental techniques stated. A multiple-addition mixing technique for investigation of the equilibria, together with the neccessary ancillary techniques, has been developed and an exhaustive mathematical analysis of the results, using a specially written computer programme, described. A detailed validation of the techniques has been carried out and their particular advantages and disadvantages compared with other techniques.</p> <p>The multiple-addition mixing technique has been used to investigate the effects of pH on the parameters of some of the more important models for the haemoglobin- oxygen equilibria and the results compared with those predicted from theoretical considerations.</p> <p>None of the models considered emerged as a complete description of the data obtained and guidelines for the development of new models have been given.</p> |
| spellingShingle | Seaton, B The respiratory functions of blood |
| title | The respiratory functions of blood |
| title_full | The respiratory functions of blood |
| title_fullStr | The respiratory functions of blood |
| title_full_unstemmed | The respiratory functions of blood |
| title_short | The respiratory functions of blood |
| title_sort | respiratory functions of blood |
| work_keys_str_mv | AT seatonb therespiratoryfunctionsofblood AT seatonb respiratoryfunctionsofblood |