Interleukin-1 beta gene deregulation associated with chromosomal rearrangement: a candidate initiating event for murine radiation-myeloid leukemogenesis?

The incidence of acute myeloid leukemia (AML) in CBA/H mice following exposure to single acute doses of ionizing radiation has previously been determined. A high proportion of these AMLs are characterized by rearrangement of murine chromosome 2 in the C2 and/or E5-F regions, and there is evidence th...

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Bibliographic Details
Main Authors: Silver, A, Boultwood, J, Breckon, G, Masson, W, Adam, J, Shaw, A, Cox, R
Format: Journal article
Language:English
Published: 1989