A common LPA null allele associates with lower lipoprotein(a) levels and coronary artery disease risk.
OBJECTIVE: Increased levels of lipoprotein(a) are a highly heritable risk factor for coronary artery disease (CAD). The genetic determinants of lipoprotein(a) levels are mainly because of genetic variation in the apolipoprotein(a) gene (LPA). We have tested the association of a relatively common nul...
Main Authors: | Kyriakou, T, Seedorf, U, Goel, A, Hopewell, J, Clarke, R, Watkins, H, Farrall, M |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2014
|
Similar Items
-
A common LPA null allele associates with lower lipoprotein(a) levels and coronary artery disease risk
by: Kyriakou, T, et al.
Published: (2014) -
LPA NULL MUTATION GENOTYPING AND QPCR ANALYSIS REFINE KRINGLE ISOFORM ANALYSIS OF LP(A) LEVELS
by: Kyriakou, T, et al.
Published: (2014) -
Impact of lipoprotein(a) levels and apolipoprotein(a) isoform size on risk of coronary heart disease
by: Hopewell, J, et al.
Published: (2014) -
Impact of lipoprotein(a) levels and apolipoprotein(a) isoform size on risk of coronary heart disease.
by: Hopewell, J, et al.
Published: (2014) -
Association of Apolipoprotein(a) Isoforms With Coronary Heart Disease is Mediated Through Plasma Lipoprotein(a) Levels
by: Hopewell, J, et al.
Published: (2010)