Reduced amounts and abnormal forms of phospholipase C zeta (PLCzeta) in spermatozoa from infertile men.

BACKGROUND: In mammals, oocyte activation at fertilization is thought to be induced by the sperm-specific phospholipase C zeta (PLCzeta). However, it still remains to be conclusively shown that PLCzeta is the endogenous agent of oocyte activation. Some types of human infertility appear to be caused...

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Autori principali: Heytens, E, Parrington, J, Coward, K, Young, C, Lambrecht, S, Yoon, S, Fissore, R, Hamer, R, Deane, C, Ruas, M, Grasa, P, Soleimani, R, Cuvelier, C, Gerris, J, Dhont, M, Deforce, D, Leybaert, L, De Sutter, P
Natura: Journal article
Lingua:English
Pubblicazione: 2009