Non-inherited maternal HLA alleles are associated with rheumatoid arthritis.

Non-inherited maternal HLA alleles are associated with rheumatoid arthritis.

BACKGROUND: Rheumatoid arthritis (RA) is strongly associated with a series of HLA-DRB1 alleles that encode a conserved sequence of amino acids ((70)Q/R K/R R A A(74)) in the DRbeta1 chain, known as the shared epitope (SE). However 30% of patients are negative for DRB1*04 and 15% are SE-negative. Exp...

书目详细资料
Main Authors:	Harney, S, Newton, J, Milicic, A, Brown, M, Wordsworth, B
格式:	Journal article
语言:	English
出版:	2003

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