Non-inherited maternal HLA alleles are associated with rheumatoid arthritis.

Non-inherited maternal HLA alleles are associated with rheumatoid arthritis.

BACKGROUND: Rheumatoid arthritis (RA) is strongly associated with a series of HLA-DRB1 alleles that encode a conserved sequence of amino acids ((70)Q/R K/R R A A(74)) in the DRbeta1 chain, known as the shared epitope (SE). However 30% of patients are negative for DRB1*04 and 15% are SE-negative. Exp...

Полное описание

Библиографические подробности
Главные авторы:	Harney, S, Newton, J, Milicic, A, Brown, M, Wordsworth, B
Формат:	Journal article
Язык:	English
Опубликовано:	2003

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