FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma.

FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma.

FOXP3 is a forkhead transcription factor family member, implicated in T-cell regulation, activation and differentiation. FOXP3 has been shown to be a master control gene for the development and function of CD4+/CD25+ regulatory T-cells (T(reg)). In this study, FOXP3 protein expression has been analy...

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Príomhchruthaitheoirí:	Roncador, G, Garcia, J, Maestre, L, Lucas, E, Menarguez, J, Ohshima, K, Nakamura, S, Banham, A, Piris, M
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2005

Míreanna comhchosúla

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Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma.
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Monoclonal antibodies raised to the human FOXP3 protein can be used effectively for detecting Foxp3(+) T cells in other mammalian species.
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