Cone photoreceptor neuroprotection conferred by CNTF in a novel in vivo model of battlefield retinal laser injury.

Cone photoreceptor neuroprotection conferred by CNTF in a novel in vivo model of battlefield retinal laser injury.

PURPOSE: To develop a reproducible laboratory model to simulate a battlefield foveal laser injury and to test potential neuroprotective effects of a single injection treatment that might be administered in a military setting. METHODS: Frequency-doubled 532-nm Nd:YAG laser was used to induce a thres...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Aslam, SA, Davies, W, Singh, MS, Charbel Issa, P, Barnard, A, Scott, R, Maclaren, R
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2013

Eitemau Tebyg

AAV-Mediated Expression of Secreted Human Ciliary Neurotropic Factor (hCNTF) Leads to Long-Term Preservation of Cone Photoreceptors in an Autosomal Recessive Model of Retinitis Pigmentosa
gan: Lipinski, D, et al.
Cyhoeddwyd: (2013)

Neuroprotection of cone photoreceptors in retinitis pigmentosa
gan: Lipinski, D, et al.
Cyhoeddwyd: (2013)

Assessment of cone survival in response to CNTF, GDNF, and VEGF165b in a novel ex vivo model of end-stage retinitis pigmentosa.
gan: Lipinski, D, et al.
Cyhoeddwyd: (2011)

Investigations Into Bioenergetic Neuroprotection of Cone Photoreceptors: Relevance to Retinitis Pigmentosa
gan: Daniel S. Narayan, et al.
Cyhoeddwyd: (2019-11-01)

Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation.
gan: Singh, MS, et al.
Cyhoeddwyd: (2013)

Cone fusion confusion in photoreceptor transplantation
gan: MacLaren, R
Cyhoeddwyd: (2017)

CNTF induces regeneration of cone outer segments in a rat model of retinal degeneration.
gan: Yiwen Li, et al.
Cyhoeddwyd: (2010-03-01)

Dynamic in vivo quantification of rod photoreceptor degeneration using fluorescent reporter mouse models of retinitis pigmentosa
gan: Orlans, HO, et al.
Cyhoeddwyd: (2019)

Intraretinal regeneration of axotomised retinal ganglion cells after AAV mediated CNTF delivery
gan: Ali, R, et al.
Cyhoeddwyd: (2005)

Metabolic rescue of cone photoreceptors in retinitis pigmentosa
gan: Henry J Kaplan, et al.
Cyhoeddwyd: (2021-01-01)

Investigating treatment options for battlefield retinal laser injury
gan: Aslam, S, et al.
Cyhoeddwyd: (2013)

Characterization of a dominant cone degeneration in a green fluorescent protein-reporter mouse with disruption of Loci associated with human dominant retinal dystrophy.
gan: Lipinski, D, et al.
Cyhoeddwyd: (2011)

Universality of Form: The Case of Retinal Cone Photoreceptor Mosaics
gan: Alireza Beygi
Cyhoeddwyd: (2023-05-01)

Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration.
gan: Charbel Issa, P, et al.
Cyhoeddwyd: (2012)

Retinal repair by transplantation of photoreceptor precursors.
gan: Maclaren, R, et al.
Cyhoeddwyd: (2006)

Metabolic transcriptomics dictate responses of cone photoreceptors to retinitis pigmentosa
gan: Sang Joon Lee, et al.
Cyhoeddwyd: (2025-01-01)

Metabolic transcriptomics dictate responses of cone photoreceptors to retinitis pigmentosa
gan: San Joon Lee, et al.
Cyhoeddwyd: (2023-09-01)

Expression of the neuroprotective factors BDNF, CNTF, and FGF-2 in normal and oxygen induced retinopathy
gan: Jifu Xin, et al.
Cyhoeddwyd: (2022-12-01)

Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.
gan: Hornan, D, et al.
Cyhoeddwyd: (2007)

Non-viral retinal gene therapy: a review.
gan: Charbel Issa, P, et al.
Cyhoeddwyd: (2012)

Automated detection of photoreceptors in in-vivo retinal images
gan: Piero Rangel-Fonseca, et al.
Cyhoeddwyd: (2016-10-01)

Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia.
gan: Tolmachova, T, et al.
Cyhoeddwyd: (2010)

Photoreceptor damage in Terson syndrome
gan: Szeligowski, T, et al.
Cyhoeddwyd: (2023)

In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration.
gan: Buch, P, et al.
Cyhoeddwyd: (2006)

Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex-vivo
gan: De Silva, S, et al.
Cyhoeddwyd: (2016)

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
gan: Singh, M, et al.
Cyhoeddwyd: (2016)

[Gene therapy for retinal dystrophies].
gan: Charbel Issa, P, et al.
Cyhoeddwyd: (2012)

Cone Photoreceptors in Diabetic Patients
gan: Ann E. Elsner, et al.
Cyhoeddwyd: (2022-03-01)

Development and degeneration of cone bipolar cells are independent of cone photoreceptors in a mouse model of retinitis pigmentosa.
gan: Miao Chen, et al.
Cyhoeddwyd: (2012-01-01)

Effect of Direct Current Electric Fields on Cone Like Retinal Photoreceptor Cells
gan: Juliana Guerra-Hühne, et al.
Cyhoeddwyd: (2022-09-01)

A positive feedback synapse from retinal horizontal cells to cone photoreceptors.
gan: Skyler L Jackman, et al.
Cyhoeddwyd: (2011-05-01)

Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.
gan: Jin Yang, et al.
Cyhoeddwyd: (2012-01-01)

Retinal cadherins and the retinal cadherinopathies: current concepts and future directions
gan: Yusuf, I, et al.
Cyhoeddwyd: (2022)

Neuroprotective Effect of a CNTF-Expressing Lentiviral Vector in the Quinolinic Acid Rat Model of Huntington's Disease
gan: L.Pereira de Almeida, et al.
Cyhoeddwyd: (2001-06-01)

Association of retinal nerve fiber abnormalities with serum CNTF and cognitive functions in schizophrenia patients
gan: Yanhong Liu, et al.
Cyhoeddwyd: (2020-06-01)

CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium.
gan: Rong Li, et al.
Cyhoeddwyd: (2011-01-01)

Neuroprotective gene therapy for the treatment of inherited retinal degeneration.
gan: Buch, P, et al.
Cyhoeddwyd: (2007)

Characterization, Stability, and In Vivo Efficacy Studies of Recombinant Human CNTF and Its Permeation into the Neural Retina in Ex Vivo Organotypic Retinal Explant Culture Models
gan: Jaakko Itkonen, et al.
Cyhoeddwyd: (2020-06-01)

Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids
gan: Jinlun Bai, et al.
Cyhoeddwyd: (2023-11-01)

Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells
gan: Saeed Khalili, et al.
Cyhoeddwyd: (2018-12-01)