Differential sensitivity of mouse strains to an N-alkylated imino sugar: glycosphingolipid metabolism and acrosome formation.
This review deals with the pharmacological properties of an alkylated monosaccharide mimetic, N-butyldeoxynojirimycin (NB-DNJ). This compound is of pharmacogenetic interest because one of its biological effects in mice - impairment of spermatogenesis, leading to male infertility - depends greatly on...
Հիմնական հեղինակներ: | van der Spoel, A, Mott, R, Platt, F |
---|---|
Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2008
|
Նմանատիպ նյութեր
-
Pharmacological impairment of acrosome formation and sperm head morphogenesis reveals essential role of glycosphingolipids in spermiogenesis
: van der Spoel, A, և այլն
Հրապարակվել է: (2002) -
Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells.
: Boomkamp, S, և այլն
Հրապարակվել է: (2010) -
Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
: Butters, T, և այլն
Հրապարակվել է: (2000) -
Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception.
: van der Spoel, A, և այլն
Հրապարակվել է: (2002) -
Alkylated imino sugars, reversible male infertility-inducing agents, do not change the genetic integrity of male mouse germ cells, despite severe deformities of spermatozoal structures.
: Suganuma, R, և այլն
Հրապարակվել է: (2004)