Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin- mediated endothelial nitric oxide synthase coupling

Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin- mediated endothelial nitric oxide synthase coupling

عرض إصدارات أخرى (1)

Background-: Treatment with statins improves clinical outcome, but the exact mechanisms of pleiotropic statin effects on vascular function in human atherosclerosis remain unclear. We examined the direct effects of atorvastatin on tetrahydrobiopterin-mediated endothelial nitric oxide (NO) synthase co...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Antoniades, C, Bakogiannis, C, Leeson, P, Guzik, T, Zhang, M, Tousoulis, D, Antonopoulos, A, Demosthenous, M, Marinou, K, Hale, A, Paschalis, A, Psarros, C, Triantafyllou, C, Bendall, J, Casadei, B, Stefanadis, C, Channon, K
التنسيق:	Journal article
اللغة:	English
منشور في:	2011

مواد مشابهة

Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling.
حسب: Antoniades, C, وآخرون
منشور في: (2011)

Statin treatment improves vascular redox state through a tetrahydrobiopterin-mediated re-coupling of endothelial nitric oxide synthase, in human atherosclerosis
حسب: Antoniades, C, وآخرون
منشور في: (2011)

RAPID, DIRECT EFFECTS OF STATIN TREATMENT ON ARTERIAL REDOX STATE AND NITRIC OXIDE BIOAVAILABILITY IN HUMAN ATHEROSCLEROSIS VIA TETRAHYDROBIOPTERIN-MEDIATED ENOS COUPLING
حسب: Antoniades, C, وآخرون
منشور في: (2011)

Atorvastatin rapidly modifies vascular redox state and improves nitric oxide bioavailability in human vessels obtained from patients with advanced atherosclerosis
حسب: Demosthenous, M, وآخرون
منشور في: (2010)

Rapid Effects of Atorvastatin on Tetrahydrobiopterin-Mediated eNOS Coupling in Human Arteries, is Mediated by Stimulation of Vascular GTP-Cyclohydrolase
حسب: Antoniades, C, وآخرون
منشور في: (2011)

Myocardial Redox State Predicts Post-Operative Clinical Outcome in Patients Undergoing Elective CABG: The Role of NADPH-Oxidase and Uncoupled Nitric Oxide Synthase
حسب: Antoniades, C, وآخرون
منشور في: (2010)

Mechanisms regulating myocardial redox state in chronic atrial fibrillation: the role of NADPH-oxidase and uncoupled nitric oxide synthases
حسب: Margaritis, M, وآخرون
منشور في: (2010)

Endothelial nitric oxide synthase in the vascular wall: Mechanisms regulating its expression and enzymatic function
حسب: Demosthenous, M, وآخرون
منشور في: (2011)

Endothelial nitric oxide synthase in the vascular wall: Mechanisms regulating its expression and enzymatic function
حسب: Demosthenous, M, وآخرون
منشور في: (2011)

Tetrahydrobiopterin and nitric oxide synthase recouplers
حسب: Channon, KM
منشور في: (2020)

Plasma asymmetrical-dimethyl-arginine (ADMA) regulates nitric oxide bioavailability and vascular superoxide production in human vessels
حسب: Antoniades, C, وآخرون
منشور في: (2007)

Plasma asymmetrical-dimethyl-arginine (ADMA) as a regulator of vascular redox and nitric oxide bioavailability in human vessels
حسب: Antoniades, C, وآخرون
منشور في: (2007)

Nitric oxide-releasing aspirin: will it say NO to atherothrombosis?
حسب: Antoniades, C, وآخرون
منشور في: (2007)

Short-Term Atorvastatin Treatment Reduces Vascular Oxidative Stress Saphenous Vein Grafts by Improving eNOS Coupling and Reducing NADPH-Oxidase Activity in Patients Undergoing Elective CABG
حسب: Antoniades, C, وآخرون
منشور في: (2009)

Nitric oxide in coronary artery disease: Effects of antioxidants
حسب: Tousoulis, D, وآخرون
منشور في: (2006)

Plasma asymmetrical-dimethyl-arginine affects eNOS vascular superoxide radical production and nitric oxide bioavailability in human arteries and veins
حسب: Antoniades, C, وآخرون
منشور في: (2008)

Endothelial nitric oxide synthase in the vascular wall: Mechanisms regulating its expression and enzymatic function
حسب: Michael Demosthenous, وآخرون
منشور في: (2011-04-01)

Oral Atorvastatin Treatment Improves NO Bioavailability and Vascular Redox State in the Human Arterial Wall, via a Tetrahydrobiopterin-Mediated Improvement of eNOS Coupling
حسب: Antoniades, C, وآخرون
منشور في: (2011)

Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis.
حسب: Antoniades, C, وآخرون
منشور في: (2011)

Induction of vascular GTP-cyclohydrolase i and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis
حسب: Antoniades, C, وآخرون
منشور في: (2011)

Tetrahydrobiopterin deficiency uncouples nitric oxide synthase and causes pulmonary hypertension
حسب: Khoo, J, وآخرون
منشور في: (2004)

Polymorphism of MTHFR gene affects vascular redox and nitric oxide bioavailability by modifying eNOS coupling
حسب: Antoniades, C, وآخرون
منشور في: (2008)

5-methyl-tetrahydrofolic acid increases nitric oxide bioavailability and decreases superoxide production by improving eNOS coupling in human vessels in vivo: Effects on intracellular tetrahydrobiopterin oxidation
حسب: Antoniades, C, وآخرون
منشور في: (2006)

Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease.
حسب: Channon, K
منشور في: (2004)

Tetrahydrobiopterin: coupling nitric oxide and redox signalling in cardiovascular disease
حسب: Channon, K
منشور في: (2012)

Genetic Polymorphism On Methyl-Tetrahydrofolate-Reductase Affects Vascular Superoxide Generation and Nitric Oxide Bioavailability By Regulating eNOS Coupling in Human Arteries and Veins
حسب: Antoniades, C, وآخرون
منشور في: (2009)

Genetic variability of MTHFR affects vascular redox and nitric oxide bioavailability in human vessels, by modifying eNOS coupling
حسب: Antoniades, C, وآخرون
منشور في: (2008)

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
حسب: Alp, N, وآخرون
منشور في: (2004)

Adiponectin as a Biomarker at Different Stages of Ischaemic Heart Disease: From Obesity to Ischaemic Heart Failure
حسب: Antonopoulos, A, وآخرون
منشور في: (2009)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
حسب: Crabtree, M, وآخرون
منشور في: (2011)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
حسب: Crabtree, M, وآخرون
منشور في: (2011)

Acute Inflammation Rapidly Increases Plasma Biopterins and Impairs Endothelial Function: A Novel Role of Plasma Tetrahydrobiopterin as a Marker of Acute Inflammation
حسب: Antonopoulos, A, وآخرون
منشور في: (2011)

Interrelationships between vascular superoxide and adiponectin biosynthesis in perivascular adipose tissue in human atherosclerosis
حسب: Bakogiannis, C, وآخرون
منشور في: (2010)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
حسب: Alp, N, وآخرون
منشور في: (2003)

Tetrahydrobiopterin Prevents Lung Ischemia/reperfusion-Induced Uncoupling of Endothelial Nitric Oxide Synthase
حسب: Juni, R, وآخرون
منشور في: (2012)

Effects of endothelial nitric oxide synthase gene polymorphisms on oxidative stress, inflammatory status, and coronary atherosclerosis: an example of a transient phenotype.
حسب: Antoniades, C, وآخرون
منشور في: (2007)

Statins ameliorate atherosclerosis induced by inhibition of nitric oxide synthase: another novel vascular protective mechanism?
حسب: Tousoulis, D, وآخرون
منشور في: (2008)

Endothelial tetrahydrobiopterin deficiency accelerates atherosclerotic progression by nitric oxide synthase uncoupling
حسب: Khoo, J, وآخرون
منشور في: (2005)

Novel therapeutic strategies targeting vascular redox in human atherosclerosis.
حسب: Antonopoulos, A, وآخرون
منشور في: (2009)

P683The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy.
حسب: Duglan, D, وآخرون
منشور في: (2014)