Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin- mediated endothelial nitric oxide synthase coupling

Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin- mediated endothelial nitric oxide synthase coupling

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Background-: Treatment with statins improves clinical outcome, but the exact mechanisms of pleiotropic statin effects on vascular function in human atherosclerosis remain unclear. We examined the direct effects of atorvastatin on tetrahydrobiopterin-mediated endothelial nitric oxide (NO) synthase co...

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Bibliographic Details
Main Authors:	Antoniades, C, Bakogiannis, C, Leeson, P, Guzik, T, Zhang, M, Tousoulis, D, Antonopoulos, A, Demosthenous, M, Marinou, K, Hale, A, Paschalis, A, Psarros, C, Triantafyllou, C, Bendall, J, Casadei, B, Stefanadis, C, Channon, K
Format:	Journal article
Language:	English
Published:	2011

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