Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy.

Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy.

Induction and maintenance of cytotoxic T lymphocyte (CTL) activity specific for a primary endogenous tumor was investigated in vivo. The simian virus 40 T antigen (Tag) expressed under the control of the rat insulin promoter (RIP) induced pancreatic beta-cell tumors producing insulin, causing progre...

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Bibliographic Details
Main Authors:	Speiser, D, Miranda, R, Zakarian, A, Bachmann, M, McKall-Faienza, K, Odermatt, B, Hanahan, D, Zinkernagel, R, Ohashi, P
Format:	Journal article
Language:	English
Published:	1997

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