Single point mutations in ATP synthase compensate for mitochondrial genome loss in trypanosomes
Viability of the tsetse fly-transmitted African trypanosome Trypanosoma brucei depends on maintenance and expression of its kinetoplast (kDNA), the mitochondrial genome of this parasite and a putative target for veterinary and human antitrypanosomatid drugs. However, the closely related animal patho...
Main Authors: | Dean, S, Gould, MK, Dewar, CE, Schnaufer, AC |
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Format: | Journal article |
Jezik: | English |
Izdano: |
National Academy of Sciences
2013
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