Cellular reprogramming: a new approach to modelling Parkinson's disease.

Cellular reprogramming: a new approach to modelling Parkinson's disease.

iPSCs (induced pluripotent stem cells) offer an unparalleled opportunity to generate and study physiologically relevant cell types in culture. iPSCs can be generated by reprogramming almost any somatic cell type using pluripotency factors such as Oct4, SOX2, Nanog and Klf4. By reprogramming cells fr...

Podrobná bibliografie
Hlavní autoři:	Hartfield, E, Fernandes, H, Vowles, J, Cowley, S, Wade-Martins, R
Médium:	Journal article
Jazyk:	English
Vydáno:	2012

Podobné jednotky

Physiological characterisation of human iPS-derived dopaminergic neurons
Autor: Hartfield, E, a další
Vydáno: (2014)

Physiological characterisation of human iPS-derived dopaminergic neurons
Autor: Hartfield, E, a další
Vydáno: (2014)

Parkinson's disease in a dish - Using stem cells as a molecular tool.
Autor: Badger, J, a další
Vydáno: (2014)

Parkinson's disease in a dish - Using stem cells as a molecular tool
Autor: Badger, J, a další
Vydáno: (2014)

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons
Autor: Zambon, F, a další
Vydáno: (2019)

Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease
Autor: Keane, H, a další
Vydáno: (2015)

Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.
Autor: Vazquez-Arango, P, a další
Vydáno: (2016)

Physiological characterisation of human iPS-derived dopaminergic neurons.
Autor: Elizabeth M Hartfield, a další
Vydáno: (2014-01-01)

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Autor: Sandor, C, a další
Vydáno: (2017)

Cell reprogramming therapy for Parkinson’s disease
Autor: Wenjing Dong, a další
Vydáno: (2024-01-01)

ER stress and autophagic perturbations lead to elevated extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons
Autor: Fernandes, H, a další
Vydáno: (2016)

Cellular reprogramming for understanding and treating human disease.
Autor: Riya Rajan Kanherkar, a další
Vydáno: (2014-11-01)

Neuroprotective Effects of Cryptotanshinone in a Direct Reprogramming Model of Parkinson’s Disease
Autor: Joo-Eun Lee, a další
Vydáno: (2020-08-01)

Epigenetic Dynamics in Reprogramming to Dopaminergic Neurons for Parkinson's Disease
Autor: Byounggook Cho, a další
Vydáno: (2024-11-01)

Astrocyte-to-neuron reprogramming and crosstalk in the treatment of Parkinson's disease
Autor: Yiming Wang, a další
Vydáno: (2023-08-01)

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models
Autor: Fernandes, H, a další
Vydáno: (2017)

Are rodent models of Parkinson's disease behaving as they should?
Autor: Vingill, S, a další
Vydáno: (2017)

Cellular Reprogramming and Its Potential Application in Alzheimer’s Disease
Autor: Chao Zhou, a další
Vydáno: (2022-04-01)

Network pharmacology of the MPP+ cellular model of Parkinson’s disease
Autor: Keane, H
Vydáno: (2015)

RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes
Autor: Booth, H, a další
Vydáno: (2019)

Programming and reprogramming cellular identity
Autor: Marson, Alexander
Vydáno: (2008)

Re: Epigenetics of Cellular Reprogramming
Autor: Fehmi Narter
Vydáno: (2016-12-01)

Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique
Autor: Anastasia M. Yunusova, a další
Vydáno: (2017-01-01)

Convergent pathways in Parkinson’s disease
Autor: Cherubini, M, a další
Vydáno: (2017)

Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair
Autor: Xingyu He, a další
Vydáno: (2022-12-01)

Potential cellular and regenerative approaches for the treatment of Parkinson&rsquo;s disease
Autor: Emma L Lane, a další
Vydáno: (2008-08-01)

Cellular Reprogramming toward the Erythroid Lineage
Autor: Laura J. Norton, a další
Vydáno: (2011-01-01)

Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes
Autor: Lang, C, a další
Vydáno: (2018)

Epigenetic reprogramming shapes the cellular landscape of schwannoma
Autor: S. John Liu, a další
Vydáno: (2024-01-01)

Epigenetic determinants of cellular differentiation, transcriptional reprogramming, and human disease
Autor: Nguyen, Khoi Thien.
Vydáno: (2021)

The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming
Autor: Bharathi Suresh, a další
Vydáno: (2016-01-01)

Dynamical systems theory of cellular reprogramming
Autor: Yuuki Matsushita, a další
Vydáno: (2022-04-01)

Cellular programming and reprogramming - Methods and protocols
Autor: CarloAlberto Redi
Vydáno: (2010-12-01)

Implications of Cellular Aging in Cardiac Reprogramming
Autor: Fabiana Passaro, a další
Vydáno: (2018-04-01)

Neuroregeneration using in vivo cellular reprogramming
Autor: Tu Nguyen, a další
Vydáno: (2017-01-01)

The role of astrocyte dysfunction in Parkinson's disease pathogenesis
Autor: Booth, H, a další
Vydáno: (2017)

Induced pluripotent stem cell (iPSC)-derived dopaminergic models of Parkinson's disease.
Autor: Beevers, J, a další
Vydáno: (2013)

Parkinson’s Disease in a Dish: What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson’s Disease, If Anything?
Autor: J. Drouin-Ouellet, a další
Vydáno: (2012-01-01)

Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson’s Disease
Autor: Marta Lualdi, a další
Vydáno: (2019-07-01)

New roles of glycosaminoglycans in α-synuclein aggregation in a cellular model of Parkinson disease.
Autor: Sonia Lehri-Boufala, a další
Vydáno: (2015-01-01)