Cellular reprogramming: a new approach to modelling Parkinson's disease.

Cellular reprogramming: a new approach to modelling Parkinson's disease.

iPSCs (induced pluripotent stem cells) offer an unparalleled opportunity to generate and study physiologically relevant cell types in culture. iPSCs can be generated by reprogramming almost any somatic cell type using pluripotency factors such as Oct4, SOX2, Nanog and Klf4. By reprogramming cells fr...

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Bibliografiske detaljer
Main Authors:	Hartfield, E, Fernandes, H, Vowles, J, Cowley, S, Wade-Martins, R
Format:	Journal article
Sprog:	English
Udgivet:	2012

Lignende værker

Physiological characterisation of human iPS-derived dopaminergic neurons
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Udgivet: (2014)

Physiological characterisation of human iPS-derived dopaminergic neurons
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Parkinson's disease in a dish - Using stem cells as a molecular tool.
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Parkinson's disease in a dish - Using stem cells as a molecular tool
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Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons
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Udgivet: (2019)

Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease
af: Keane, H, et al.
Udgivet: (2015)

Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.
af: Vazquez-Arango, P, et al.
Udgivet: (2016)

Physiological characterisation of human iPS-derived dopaminergic neurons.
af: Elizabeth M Hartfield, et al.
Udgivet: (2014-01-01)

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
af: Sandor, C, et al.
Udgivet: (2017)

Cell reprogramming therapy for Parkinson’s disease
af: Wenjing Dong, et al.
Udgivet: (2024-01-01)

ER stress and autophagic perturbations lead to elevated extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons
af: Fernandes, H, et al.
Udgivet: (2016)

Cellular reprogramming for understanding and treating human disease.
af: Riya Rajan Kanherkar, et al.
Udgivet: (2014-11-01)

Neuroprotective Effects of Cryptotanshinone in a Direct Reprogramming Model of Parkinson’s Disease
af: Joo-Eun Lee, et al.
Udgivet: (2020-08-01)

Epigenetic Dynamics in Reprogramming to Dopaminergic Neurons for Parkinson's Disease
af: Byounggook Cho, et al.
Udgivet: (2024-11-01)

Astrocyte-to-neuron reprogramming and crosstalk in the treatment of Parkinson's disease
af: Yiming Wang, et al.
Udgivet: (2023-08-01)

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models
af: Fernandes, H, et al.
Udgivet: (2017)

Are rodent models of Parkinson's disease behaving as they should?
af: Vingill, S, et al.
Udgivet: (2017)

Cellular Reprogramming and Its Potential Application in Alzheimer’s Disease
af: Chao Zhou, et al.
Udgivet: (2022-04-01)

Network pharmacology of the MPP+ cellular model of Parkinson’s disease
af: Keane, H
Udgivet: (2015)

RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes
af: Booth, H, et al.
Udgivet: (2019)

Programming and reprogramming cellular identity
af: Marson, Alexander
Udgivet: (2008)

Re: Epigenetics of Cellular Reprogramming
af: Fehmi Narter
Udgivet: (2016-12-01)

Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique
af: Anastasia M. Yunusova, et al.
Udgivet: (2017-01-01)

Convergent pathways in Parkinson’s disease
af: Cherubini, M, et al.
Udgivet: (2017)

Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair
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Udgivet: (2022-12-01)

Potential cellular and regenerative approaches for the treatment of Parkinson&rsquo;s disease
af: Emma L Lane, et al.
Udgivet: (2008-08-01)

Cellular Reprogramming toward the Erythroid Lineage
af: Laura J. Norton, et al.
Udgivet: (2011-01-01)

Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes
af: Lang, C, et al.
Udgivet: (2018)

Epigenetic reprogramming shapes the cellular landscape of schwannoma
af: S. John Liu, et al.
Udgivet: (2024-01-01)

Epigenetic determinants of cellular differentiation, transcriptional reprogramming, and human disease
af: Nguyen, Khoi Thien.
Udgivet: (2021)

The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming
af: Bharathi Suresh, et al.
Udgivet: (2016-01-01)

Dynamical systems theory of cellular reprogramming
af: Yuuki Matsushita, et al.
Udgivet: (2022-04-01)

Cellular programming and reprogramming - Methods and protocols
af: CarloAlberto Redi
Udgivet: (2010-12-01)

Implications of Cellular Aging in Cardiac Reprogramming
af: Fabiana Passaro, et al.
Udgivet: (2018-04-01)

Neuroregeneration using in vivo cellular reprogramming
af: Tu Nguyen, et al.
Udgivet: (2017-01-01)

The role of astrocyte dysfunction in Parkinson's disease pathogenesis
af: Booth, H, et al.
Udgivet: (2017)

Induced pluripotent stem cell (iPSC)-derived dopaminergic models of Parkinson's disease.
af: Beevers, J, et al.
Udgivet: (2013)

Parkinson’s Disease in a Dish: What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson’s Disease, If Anything?
af: J. Drouin-Ouellet, et al.
Udgivet: (2012-01-01)

Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson’s Disease
af: Marta Lualdi, et al.
Udgivet: (2019-07-01)

New roles of glycosaminoglycans in α-synuclein aggregation in a cellular model of Parkinson disease.
af: Sonia Lehri-Boufala, et al.
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