Cellular reprogramming: a new approach to modelling Parkinson's disease.

Cellular reprogramming: a new approach to modelling Parkinson's disease.

iPSCs (induced pluripotent stem cells) offer an unparalleled opportunity to generate and study physiologically relevant cell types in culture. iPSCs can be generated by reprogramming almost any somatic cell type using pluripotency factors such as Oct4, SOX2, Nanog and Klf4. By reprogramming cells fr...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Hartfield, E, Fernandes, H, Vowles, J, Cowley, S, Wade-Martins, R
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2012

समान संसाधन

Physiological characterisation of human iPS-derived dopaminergic neurons
द्वारा: Hartfield, E, और अन्य
प्रकाशित: (2014)

Physiological characterisation of human iPS-derived dopaminergic neurons
द्वारा: Hartfield, E, और अन्य
प्रकाशित: (2014)

Parkinson's disease in a dish - Using stem cells as a molecular tool.
द्वारा: Badger, J, और अन्य
प्रकाशित: (2014)

Parkinson's disease in a dish - Using stem cells as a molecular tool
द्वारा: Badger, J, और अन्य
प्रकाशित: (2014)

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons
द्वारा: Zambon, F, और अन्य
प्रकाशित: (2019)

Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease
द्वारा: Keane, H, और अन्य
प्रकाशित: (2015)

Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.
द्वारा: Vazquez-Arango, P, और अन्य
प्रकाशित: (2016)

Physiological characterisation of human iPS-derived dopaminergic neurons.
द्वारा: Elizabeth M Hartfield, और अन्य
प्रकाशित: (2014-01-01)

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
द्वारा: Sandor, C, और अन्य
प्रकाशित: (2017)

Cell reprogramming therapy for Parkinson’s disease
द्वारा: Wenjing Dong, और अन्य
प्रकाशित: (2024-01-01)

ER stress and autophagic perturbations lead to elevated extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons
द्वारा: Fernandes, H, और अन्य
प्रकाशित: (2016)

Cellular reprogramming for understanding and treating human disease.
द्वारा: Riya Rajan Kanherkar, और अन्य
प्रकाशित: (2014-11-01)

Neuroprotective Effects of Cryptotanshinone in a Direct Reprogramming Model of Parkinson’s Disease
द्वारा: Joo-Eun Lee, और अन्य
प्रकाशित: (2020-08-01)

Epigenetic Dynamics in Reprogramming to Dopaminergic Neurons for Parkinson's Disease
द्वारा: Byounggook Cho, और अन्य
प्रकाशित: (2024-11-01)

Astrocyte-to-neuron reprogramming and crosstalk in the treatment of Parkinson's disease
द्वारा: Yiming Wang, और अन्य
प्रकाशित: (2023-08-01)

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models
द्वारा: Fernandes, H, और अन्य
प्रकाशित: (2017)

Are rodent models of Parkinson's disease behaving as they should?
द्वारा: Vingill, S, और अन्य
प्रकाशित: (2017)

Cellular Reprogramming and Its Potential Application in Alzheimer’s Disease
द्वारा: Chao Zhou, और अन्य
प्रकाशित: (2022-04-01)

Network pharmacology of the MPP+ cellular model of Parkinson’s disease
द्वारा: Keane, H
प्रकाशित: (2015)

RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes
द्वारा: Booth, H, और अन्य
प्रकाशित: (2019)

Programming and reprogramming cellular identity
द्वारा: Marson, Alexander
प्रकाशित: (2008)

Re: Epigenetics of Cellular Reprogramming
द्वारा: Fehmi Narter
प्रकाशित: (2016-12-01)

Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique
द्वारा: Anastasia M. Yunusova, और अन्य
प्रकाशित: (2017-01-01)

Convergent pathways in Parkinson’s disease
द्वारा: Cherubini, M, और अन्य
प्रकाशित: (2017)

Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair
द्वारा: Xingyu He, और अन्य
प्रकाशित: (2022-12-01)

Potential cellular and regenerative approaches for the treatment of Parkinson&rsquo;s disease
द्वारा: Emma L Lane, और अन्य
प्रकाशित: (2008-08-01)

Cellular Reprogramming toward the Erythroid Lineage
द्वारा: Laura J. Norton, और अन्य
प्रकाशित: (2011-01-01)

Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes
द्वारा: Lang, C, और अन्य
प्रकाशित: (2018)

Epigenetic reprogramming shapes the cellular landscape of schwannoma
द्वारा: S. John Liu, और अन्य
प्रकाशित: (2024-01-01)

Epigenetic determinants of cellular differentiation, transcriptional reprogramming, and human disease
द्वारा: Nguyen, Khoi Thien.
प्रकाशित: (2021)

The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming
द्वारा: Bharathi Suresh, और अन्य
प्रकाशित: (2016-01-01)

Dynamical systems theory of cellular reprogramming
द्वारा: Yuuki Matsushita, और अन्य
प्रकाशित: (2022-04-01)

Cellular programming and reprogramming - Methods and protocols
द्वारा: CarloAlberto Redi
प्रकाशित: (2010-12-01)

Implications of Cellular Aging in Cardiac Reprogramming
द्वारा: Fabiana Passaro, और अन्य
प्रकाशित: (2018-04-01)

Neuroregeneration using in vivo cellular reprogramming
द्वारा: Tu Nguyen, और अन्य
प्रकाशित: (2017-01-01)

The role of astrocyte dysfunction in Parkinson's disease pathogenesis
द्वारा: Booth, H, और अन्य
प्रकाशित: (2017)

Induced pluripotent stem cell (iPSC)-derived dopaminergic models of Parkinson's disease.
द्वारा: Beevers, J, और अन्य
प्रकाशित: (2013)

Parkinson’s Disease in a Dish: What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson’s Disease, If Anything?
द्वारा: J. Drouin-Ouellet, और अन्य
प्रकाशित: (2012-01-01)

Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson’s Disease
द्वारा: Marta Lualdi, और अन्य
प्रकाशित: (2019-07-01)

New roles of glycosaminoglycans in α-synuclein aggregation in a cellular model of Parkinson disease.
द्वारा: Sonia Lehri-Boufala, और अन्य
प्रकाशित: (2015-01-01)