Cellular reprogramming: a new approach to modelling Parkinson's disease.

Cellular reprogramming: a new approach to modelling Parkinson's disease.

iPSCs (induced pluripotent stem cells) offer an unparalleled opportunity to generate and study physiologically relevant cell types in culture. iPSCs can be generated by reprogramming almost any somatic cell type using pluripotency factors such as Oct4, SOX2, Nanog and Klf4. By reprogramming cells fr...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Hartfield, E, Fernandes, H, Vowles, J, Cowley, S, Wade-Martins, R
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2012

Những quyển sách tương tự

Physiological characterisation of human iPS-derived dopaminergic neurons
Bằng: Hartfield, E, et al.
Được phát hành: (2014)

Physiological characterisation of human iPS-derived dopaminergic neurons
Bằng: Hartfield, E, et al.
Được phát hành: (2014)

Parkinson's disease in a dish - Using stem cells as a molecular tool.
Bằng: Badger, J, et al.
Được phát hành: (2014)

Parkinson's disease in a dish - Using stem cells as a molecular tool
Bằng: Badger, J, et al.
Được phát hành: (2014)

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons
Bằng: Zambon, F, et al.
Được phát hành: (2019)

Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease
Bằng: Keane, H, et al.
Được phát hành: (2015)

Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.
Bằng: Vazquez-Arango, P, et al.
Được phát hành: (2016)

Physiological characterisation of human iPS-derived dopaminergic neurons.
Bằng: Elizabeth M Hartfield, et al.
Được phát hành: (2014-01-01)

Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Bằng: Sandor, C, et al.
Được phát hành: (2017)

Cell reprogramming therapy for Parkinson’s disease
Bằng: Wenjing Dong, et al.
Được phát hành: (2024-01-01)

ER stress and autophagic perturbations lead to elevated extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons
Bằng: Fernandes, H, et al.
Được phát hành: (2016)

Cellular reprogramming for understanding and treating human disease.
Bằng: Riya Rajan Kanherkar, et al.
Được phát hành: (2014-11-01)

Neuroprotective Effects of Cryptotanshinone in a Direct Reprogramming Model of Parkinson’s Disease
Bằng: Joo-Eun Lee, et al.
Được phát hành: (2020-08-01)

Epigenetic Dynamics in Reprogramming to Dopaminergic Neurons for Parkinson's Disease
Bằng: Byounggook Cho, et al.
Được phát hành: (2024-11-01)

Astrocyte-to-neuron reprogramming and crosstalk in the treatment of Parkinson's disease
Bằng: Yiming Wang, et al.
Được phát hành: (2023-08-01)

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models
Bằng: Fernandes, H, et al.
Được phát hành: (2017)

Are rodent models of Parkinson's disease behaving as they should?
Bằng: Vingill, S, et al.
Được phát hành: (2017)

Cellular Reprogramming and Its Potential Application in Alzheimer’s Disease
Bằng: Chao Zhou, et al.
Được phát hành: (2022-04-01)

Network pharmacology of the MPP+ cellular model of Parkinson’s disease
Bằng: Keane, H
Được phát hành: (2015)

RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes
Bằng: Booth, H, et al.
Được phát hành: (2019)

Programming and reprogramming cellular identity
Bằng: Marson, Alexander
Được phát hành: (2008)

Re: Epigenetics of Cellular Reprogramming
Bằng: Fehmi Narter
Được phát hành: (2016-12-01)

Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique
Bằng: Anastasia M. Yunusova, et al.
Được phát hành: (2017-01-01)

Convergent pathways in Parkinson’s disease
Bằng: Cherubini, M, et al.
Được phát hành: (2017)

Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair
Bằng: Xingyu He, et al.
Được phát hành: (2022-12-01)

Potential cellular and regenerative approaches for the treatment of Parkinson&rsquo;s disease
Bằng: Emma L Lane, et al.
Được phát hành: (2008-08-01)

Cellular Reprogramming toward the Erythroid Lineage
Bằng: Laura J. Norton, et al.
Được phát hành: (2011-01-01)

Single-cell sequencing of iPSC-dopamine neurons reconstructs disease progression and identifies HDAC4 as a regulator of Parkinson cell phenotypes
Bằng: Lang, C, et al.
Được phát hành: (2018)

Epigenetic reprogramming shapes the cellular landscape of schwannoma
Bằng: S. John Liu, et al.
Được phát hành: (2024-01-01)

Epigenetic determinants of cellular differentiation, transcriptional reprogramming, and human disease
Bằng: Nguyen, Khoi Thien.
Được phát hành: (2021)

The Importance of Ubiquitination and Deubiquitination in Cellular Reprogramming
Bằng: Bharathi Suresh, et al.
Được phát hành: (2016-01-01)

Dynamical systems theory of cellular reprogramming
Bằng: Yuuki Matsushita, et al.
Được phát hành: (2022-04-01)

Cellular programming and reprogramming - Methods and protocols
Bằng: CarloAlberto Redi
Được phát hành: (2010-12-01)

Implications of Cellular Aging in Cardiac Reprogramming
Bằng: Fabiana Passaro, et al.
Được phát hành: (2018-04-01)

Neuroregeneration using in vivo cellular reprogramming
Bằng: Tu Nguyen, et al.
Được phát hành: (2017-01-01)

The role of astrocyte dysfunction in Parkinson's disease pathogenesis
Bằng: Booth, H, et al.
Được phát hành: (2017)

Induced pluripotent stem cell (iPSC)-derived dopaminergic models of Parkinson's disease.
Bằng: Beevers, J, et al.
Được phát hành: (2013)

Parkinson’s Disease in a Dish: What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson’s Disease, If Anything?
Bằng: J. Drouin-Ouellet, et al.
Được phát hành: (2012-01-01)

Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson’s Disease
Bằng: Marta Lualdi, et al.
Được phát hành: (2019-07-01)

New roles of glycosaminoglycans in α-synuclein aggregation in a cellular model of Parkinson disease.
Bằng: Sonia Lehri-Boufala, et al.
Được phát hành: (2015-01-01)