A solution to the 2-pyridyl organometallic cross-coupling problem: regioselective catalytic direct arylation of pyridine N-oxides.

Direct arylation reactions of pyridine N-oxides occur in excellent yield with complete selectivity for the 2-position with a wide range of aryl bromides. This reactivity permits the use of inexpensive, commercially available, and bench-stable pyridine N-oxides as replacements for problematic 2-metal...

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Bibliografiska uppgifter
Huvudupphovsmän: Campeau, L, Rousseaux, S, Fagnou, K
Materialtyp: Journal article
Språk:English
Publicerad: 2005