Impact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial.
AIM: Informing a person of their individual risk of developing a disease in the future may be sufficient to provide the person with the impetus to adopt risk reducing behaviours. The aim of this study was to determine if a personalised 10-year cardiovascular disease (CVD) risk estimate can increase...
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2011
|
| _version_ | 1826281889446494208 |
|---|---|
| author | Price, H Griffin, S Holman, R |
| author_facet | Price, H Griffin, S Holman, R |
| author_sort | Price, H |
| collection | OXFORD |
| description | AIM: Informing a person of their individual risk of developing a disease in the future may be sufficient to provide the person with the impetus to adopt risk reducing behaviours. The aim of this study was to determine if a personalised 10-year cardiovascular disease (CVD) risk estimate can increase physical activity and other risk reduction behaviours in adults at high risk of CVD. METHODS: Pilot 2 × 2 factorial randomised controlled trial conducted in Oxfordshire, UK including 194 adults at increased CVD risk (10-year CVD risk ≥ 20%) recruited from four general practices. Main outcome measure at one month was physical activity measured by accelerometer. RESULTS: Median (IQR) age was 62.3 (54.9, 66.1) years, 67% were men and 19% had known diabetes. Mean (SD) total accelerometer counts per day was 297 × 10(-3) (110 × 10(-3) ) and activity of moderate or greater intensity was undertaken for 53 (22) minutes per day. In the 185 (95%) participants attending follow-up an increase in physical activity was not seen. There was a non-significant 0.5% (p = 0.56) greater increase in accelerometer counts in those receiving personalised CVD risk estimates. No significant within or between group changes were seen at one month in estimated 10-year CVD risk. A net 7% decrease in mean LDL cholesterol (p = 0.004) was seen in the intervention group despite similar increases in new prescriptions for lipid lowering therapies. CONCLUSION: In adults at increased risk of CVD provision of personalised 10-year CVD risk estimates did not appear to increase physical activity or estimated CVD risk over a one-month period. |
| first_indexed | 2024-03-07T00:35:36Z |
| format | Journal article |
| id | oxford-uuid:81499a48-f7f6-4945-8594-bd6816d0c5b3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:35:36Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:81499a48-f7f6-4945-8594-bd6816d0c5b32022-03-26T21:29:22ZImpact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:81499a48-f7f6-4945-8594-bd6816d0c5b3EnglishSymplectic Elements at Oxford2011Price, HGriffin, SHolman, RAIM: Informing a person of their individual risk of developing a disease in the future may be sufficient to provide the person with the impetus to adopt risk reducing behaviours. The aim of this study was to determine if a personalised 10-year cardiovascular disease (CVD) risk estimate can increase physical activity and other risk reduction behaviours in adults at high risk of CVD. METHODS: Pilot 2 × 2 factorial randomised controlled trial conducted in Oxfordshire, UK including 194 adults at increased CVD risk (10-year CVD risk ≥ 20%) recruited from four general practices. Main outcome measure at one month was physical activity measured by accelerometer. RESULTS: Median (IQR) age was 62.3 (54.9, 66.1) years, 67% were men and 19% had known diabetes. Mean (SD) total accelerometer counts per day was 297 × 10(-3) (110 × 10(-3) ) and activity of moderate or greater intensity was undertaken for 53 (22) minutes per day. In the 185 (95%) participants attending follow-up an increase in physical activity was not seen. There was a non-significant 0.5% (p = 0.56) greater increase in accelerometer counts in those receiving personalised CVD risk estimates. No significant within or between group changes were seen at one month in estimated 10-year CVD risk. A net 7% decrease in mean LDL cholesterol (p = 0.004) was seen in the intervention group despite similar increases in new prescriptions for lipid lowering therapies. CONCLUSION: In adults at increased risk of CVD provision of personalised 10-year CVD risk estimates did not appear to increase physical activity or estimated CVD risk over a one-month period. |
| spellingShingle | Price, H Griffin, S Holman, R Impact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial. |
| title | Impact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial. |
| title_full | Impact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial. |
| title_fullStr | Impact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial. |
| title_full_unstemmed | Impact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial. |
| title_short | Impact of personalized cardiovascular disease risk estimates on physical activity-a randomized controlled trial. |
| title_sort | impact of personalized cardiovascular disease risk estimates on physical activity a randomized controlled trial |
| work_keys_str_mv | AT priceh impactofpersonalizedcardiovasculardiseaseriskestimatesonphysicalactivityarandomizedcontrolledtrial AT griffins impactofpersonalizedcardiovasculardiseaseriskestimatesonphysicalactivityarandomizedcontrolledtrial AT holmanr impactofpersonalizedcardiovasculardiseaseriskestimatesonphysicalactivityarandomizedcontrolledtrial |