Structure of human complement C8, a precursor to membrane attack
Complement component C8 plays a pivotal role in the formation of the membrane attack complex (MAC), an important antibacterial immune effector. C8 initiates membrane penetration and coordinates MAC pore formation. High-resolution structures of C8 subunits have provided some insight into the function...
Κύριοι συγγραφείς: | , , , , , |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
Elsevier
2011
|
Θέματα: |