The ligand-sensitive gate of a potassium channel lies close to the selectivity filter

Potassium channels selectively conduct K+ ions across cell membranes and have key roles in cell excitability. Their opening and closing can be spontaneous or controlled by membrane voltage or ligand binding. We used Ba2+ as a probe to determine the location of the ligand-sensitive gate in an inwardl...

Полное описание

Библиографические подробности
Главные авторы: Proks, P, Antcliff, J, Ashcroft, F
Формат: Journal article
Язык:English
Опубликовано: 2003