Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.

BACKGROUND: The borders of Thailand harbour the world's most multidrug resistant Plasmodium falciparum parasites. In 1984 mefloquine was introduced as treatment for uncomplicated falciparum malaria, but substantial resistance developed within 6 years. A combination of artesunate with mefloquin...

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Bibliographic Details
Main Authors:	Price, R, Uhlemann, A, Brockman, A, Mcgready, R, Ashley, E, Phaipun, L, Patel, R, Laing, K, Looareesuwan, S, White, N, Nosten, F, Krishna, S
Format:	Journal article
Language:	English
Published:	2004

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