Histone H2A monoubiquitylation and p38-MAPKs regulate immediate-early gene-like reactivation of latent retrovirus HTLV-1

It is not understood how the human T cell leukemia virus human T-lymphotropic virus-1 (HTLV-1), a retrovirus, regulates the in vivo balance between transcriptional latency and reactivation. The HTLV-1 proviral plus-strand is typically transcriptionally silent in freshly isolated peripheral blood mon...

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Detalles Bibliográficos
Autores principales: Kulkarni, A, Taylor, G, Klose, R, Schofield, C, Bangham, C
Formato: Journal article
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018