Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF

Bacteria deploy weapons to kill their neighbours during competition for resources and to aid survival within microbiomes. Colicins were the first such antibacterial system identified, yet how these bacteriocins cross the outer membrane (OM) of Escherichia coli is unknown. Here, by solving the struct...

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Main Authors: Francis, M-LR, Webby, MN, Housden, NG, Kaminska, R, Elliston, E, Chinthammit, B, Lukoyanova, N, Kleanthous, C
格式: Journal article
语言:English
出版: EMBO Press 2021