Test-retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA (macular integrity assessment) in normal eyes

PURPOSE: To assess the intrasession test-retest reliability of scotopic cyan and scotopic red fundus-controlled perimetry (FCP) in normal subjects using a modified MAIA "microperimeter" (macular integrity assessment) device. METHODS: Forty-seven normal eyes of 30 subjects (aged 33.8 years)...

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Main Authors: Pfau, M, Lindner, M, Fleckenstein, M, Finger, R, Rubin, G, Harmening, W, Morales, M, Holz, F, Schmitz-Valckenberg, S
Format: Journal article
Language:English
Published: Karger 2016
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author Pfau, M
Lindner, M
Fleckenstein, M
Finger, R
Rubin, G
Harmening, W
Morales, M
Holz, F
Schmitz-Valckenberg, S
author_facet Pfau, M
Lindner, M
Fleckenstein, M
Finger, R
Rubin, G
Harmening, W
Morales, M
Holz, F
Schmitz-Valckenberg, S
author_sort Pfau, M
collection OXFORD
description PURPOSE: To assess the intrasession test-retest reliability of scotopic cyan and scotopic red fundus-controlled perimetry (FCP) in normal subjects using a modified MAIA "microperimeter" (macular integrity assessment) device. METHODS: Forty-seven normal eyes of 30 subjects (aged 33.8 years) underwent duplicate mesopic (achromatic stimuli, 400-800 nm), scotopic cyan (505 nm), and scotopic red (627 nm) FCP, using a grid of 49 stimuli over 14° of the central retina. Test-retest reliability for pointwise sensitivity (PWS), stability of fixation, reaction time and test duration were analyzed using mixed-effects models. RESULTS: PWS test-retest reliability was good among all 3 types of retinal sensitivity assessments (coefficient of repeatability of 4.75 dB for mesopic, 5.26 dB for scotopic cyan, and 4.06 dB for scotopic red testing). While the mean sensitivity decreased with eccentricity for both mesopic and scotopic red testing, it was highest at 7° eccentricity for the scotopic cyan assessment (p < 0.001). CONCLUSIONS: The modified MAIA device allows for reliable scotopic FCP in normal subjects. Our findings suggest that testing of scotopic cyan sensitivity largely reflects rod function.
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spelling oxford-uuid:821b8be2-f42c-42c2-995f-fcc4747c95952022-03-26T21:35:01ZTest-retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA (macular integrity assessment) in normal eyesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:821b8be2-f42c-42c2-995f-fcc4747c9595EnglishSymplectic Elements at OxfordKarger2016Pfau, MLindner, MFleckenstein, MFinger, RRubin, GHarmening, WMorales, MHolz, FSchmitz-Valckenberg, SPURPOSE: To assess the intrasession test-retest reliability of scotopic cyan and scotopic red fundus-controlled perimetry (FCP) in normal subjects using a modified MAIA "microperimeter" (macular integrity assessment) device. METHODS: Forty-seven normal eyes of 30 subjects (aged 33.8 years) underwent duplicate mesopic (achromatic stimuli, 400-800 nm), scotopic cyan (505 nm), and scotopic red (627 nm) FCP, using a grid of 49 stimuli over 14° of the central retina. Test-retest reliability for pointwise sensitivity (PWS), stability of fixation, reaction time and test duration were analyzed using mixed-effects models. RESULTS: PWS test-retest reliability was good among all 3 types of retinal sensitivity assessments (coefficient of repeatability of 4.75 dB for mesopic, 5.26 dB for scotopic cyan, and 4.06 dB for scotopic red testing). While the mean sensitivity decreased with eccentricity for both mesopic and scotopic red testing, it was highest at 7° eccentricity for the scotopic cyan assessment (p < 0.001). CONCLUSIONS: The modified MAIA device allows for reliable scotopic FCP in normal subjects. Our findings suggest that testing of scotopic cyan sensitivity largely reflects rod function.
spellingShingle Pfau, M
Lindner, M
Fleckenstein, M
Finger, R
Rubin, G
Harmening, W
Morales, M
Holz, F
Schmitz-Valckenberg, S
Test-retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA (macular integrity assessment) in normal eyes
title Test-retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA (macular integrity assessment) in normal eyes
title_full Test-retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA (macular integrity assessment) in normal eyes
title_fullStr Test-retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA (macular integrity assessment) in normal eyes
title_full_unstemmed Test-retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA (macular integrity assessment) in normal eyes
title_short Test-retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA (macular integrity assessment) in normal eyes
title_sort test retest reliability of scotopic and mesopic fundus controlled perimetry using a modified maia macular integrity assessment in normal eyes
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