H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis.

H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis.

<h4>Background</h4> <p>Epigenetic changes (i.e., chromatin modifications) occur during chondrogenesis and in osteoarthritis (OA). We investigated the effect of H3K27me3 demethylase inhibition on chondrogenesis and assessed its utility in cartilage tissue engineering and in underst...

书目详细资料
Main Authors:	Yapp, C, Carr, A, Price, A, Oppermann, U, Snelling, S
格式:	Journal article
语言:	English
出版:	BioMed Central 2016

相似书籍

EPIGENETIC MODIFYING COMPOUNDS ALTER ACTIVITY OF PRIMARY HUMAN ARTICULAR CHONDROCYTES AND MESENCHYMAL STEM CELLS UNDERGOING CHONDROGENESIS
由: Snelling, S, et al.
出版: (2014)

EPIGENETIC MODIFYING COMPOUNDS AFFECT THE ACTIVITY OF PRIMARY HUMAN ARTICULAR CHONDROCYTES AND MESENCHYMAL STEM CELLS UNDERGOING CHONDROGENESIS
由: Snelling, S, et al.
出版: (2013)

Epigenetic modifying compounds alter activity of primary human articular chondrocytes and mesenchymal stem cells undergoing chondrogenesis
由: Snelling, S, et al.
出版: (2013)

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism
由: Cribbs, AP, et al.
出版: (2020)

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner
由: Welstead, G. Grant, et al.
出版: (2013)

Fibrosis—the tale of H3K27 histone methyltransferases and demethylases
由: Morgan D. Basta, et al.
出版: (2023-07-01)

The chondrocyte-intrinsic circadian clock is disrupted in human osteoarthritis
由: Snelling, S, et al.
出版: (2016)

Inhibition of histone H3K27 demethylase selectively modulates inflammatory phenotypes of natural killer cells
由: Cribbs, A, et al.
出版: (2018)

Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death
由: Cottone, L, et al.
出版: (2020)

JMJ Histone Demethylases Balance H3K27me3 and H3K4me3 Levels at the <i>HSP21</i> Locus during Heat Acclimation in <i>Arabidopsis</i>
由: Nobutoshi Yamaguchi, et al.
出版: (2021-06-01)

Interleukin-17A causes osteoarthritis-like transcriptional changes in human osteoarthritis-derived chondrocytes and synovial fibroblasts in vitro
由: Mimpen, JY, et al.
出版: (2021)

Ageing-Related Changes to H3K4me3, H3K27ac, and H3K27me3 in Purified Mouse Neurons
由: Brandon Signal, et al.
出版: (2024-08-01)

Roles of H3K27me2 and H3K27me3 Examined during Fate Specification of Embryonic Stem Cells
由: Juan, Aster H., et al.
出版: (2017)

Development of biochemical tools to characterise human H3K27 histone demethylase JmjD3
由: Che, KH
出版: (2013)

Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage
由: Tianyou Kan, et al.
出版: (2024-08-01)

H3K4me3, H3K9ac, H3K27ac, H3K27me3 and H3K9me3 Histone Tags Suggest Distinct Regulatory Evolution of Open and Condensed Chromatin Landmarks
由: Anna A. Igolkina, et al.
出版: (2019-09-01)

Directed differentiation of human induced pluripotent stem cells into chondrocytes
由: Hala, S, et al.
出版: (2011)

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
由: Kruidenier, L, et al.
出版: (2012)

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
由: Kruidenier, L, et al.
出版: (2012)

ALB–PRF facilitates chondrogenesis by promoting chondrocytes migration, proliferation and differentiation
由: Lijuan Zeng, et al.
出版: (2024-12-01)

DKK3 CAN PREVENT CARTILAGE DEGRADATION AND REGULATE CHONDROCYTE CELL SIGNALLING
由: Snelling, S, et al.
出版: (2012)

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
由: Ntziachristos, Panagiotis, et al.
出版: (2015)

Temperature-dependent jumonji demethylase modulates flowering time by targeting H3K36me2/3 in Brassica rapa
由: Xiaoyun Xin, et al.
出版: (2024-06-01)

Computational inference of H3K4me3 and H3K27ac domain length
由: Julian Zubek, et al.
出版: (2016-03-01)

Fibrin and poly(lactic-co-glycolic acid) hybrid scaffold promotes early chondrogenesis of articular chondrocytes: an in vitro study
由: Sha'ban, Munirah, et al.
出版: (2008)

Inhibiting H3K27 Demethylases Downregulates CREB‐CREBBP, Overcoming Resistance in Relapsed Acute Lymphoblastic Leukemia
由: Juan Lazaro‐Navarro, et al.
出版: (2025-01-01)

Distinct H3K27me3 and H3K27ac Modifications in Neural Tube Defects Induced by Benzo[a]pyrene
由: Shanshan Lin, et al.
出版: (2023-02-01)

The Histone H3 K4me3, K27me3, and K27ac Genome-Wide Distributions Are Differently Influenced by Sex in Brain Cortexes and Gastrocnemius of the Alzheimer’s Disease PSAPP Mouse Model
由: Francesca Casciaro, et al.
出版: (2021-11-01)

Dynamics of H3K27me3 Modification on Plant Adaptation to Environmental Cues
由: Qingwen Shen, et al.
出版: (2021-06-01)

Evidence for a role of Dickoppf-3 (Dkk3) in osteoarthritis
由: Snelling, S, et al.
出版: (2011)

Bisphenol B restrains rat leydig cell function via H3K27me3/H3K9me3 histone modifications
由: Jiayi He, et al.
出版: (2025-02-01)

Cold stress induces rapid gene-specific changes in the levels of H3K4me3 and H3K27me3 in Arabidopsis thaliana
由: Léa Faivre, et al.
出版: (2024-04-01)

The metabolic characteristics and changes of chondrocytes in vivo and in vitro in osteoarthritis
由: Miradj Siddick Adam, et al.
出版: (2024-05-01)

Inhibition of interleukin-17-induced effects in osteoarthritis - An in vitro study
由: Mimpen, J, et al.
出版: (2018)

The Histone H3K27 Demethylase REF6 Is a Positive Regulator of Light-Initiated Seed Germination in Arabidopsis
由: Yahan Wang, et al.
出版: (2023-01-01)

Alternative silencing states of transposable elements in Arabidopsis associated with H3K27me3
由: Valentin Hure, et al.
出版: (2025-01-01)

H3K27me3-mediated epigenetic regulation in pluripotency maintenance and lineage differentiation
由: Liwen Jiang, et al.
出版: (2024-08-01)

Peculiarity of transcriptional and H3K27me3 dynamics during peach bud dormancy
由: Yalin Zhao, et al.
出版: (2024-01-01)

The BAH domain of BAHD1 is a histone H3K27me3 reader
由: Dan Zhao, et al.
出版: (2016-02-01)

Dickkopf-3 is upregulated in osteoarthritis and has a chondroprotective role
由: Snelling, S, et al.
出版: (2015)