Overestimation of postpartum depression prevalence based on a 5-item version of the EPDS: Systematic review and individual participant data meta-analysis
<p><strong>Objective:</strong><br /> The Maternal Mental Health in Canada, 2018/2019 survey reported that 18% of 7,085 mothers who recently gave birth reported “feelings consistent with postpartum depression” based on scores ≥7 on a 5-item version of the Edinburgh Postpartum...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
SAGE Publications
2020
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| _version_ | 1797078960812589056 |
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| author | Thombs, B Levis, B Lyubenov, A Stein, A |
| author_facet | Thombs, B Levis, B Lyubenov, A Stein, A |
| author_sort | Thombs, B |
| collection | OXFORD |
| description | <p><strong>Objective:</strong><br />
The Maternal Mental Health in Canada, 2018/2019 survey reported that 18% of 7,085 mothers who recently gave birth reported “feelings consistent with postpartum depression” based on scores ≥7 on a 5-item version of the Edinburgh Postpartum Depression Scale (EPDS5). The EPDS-5 was designed as a screening questionnaire, not to classify disorders or estimate prevalence; the extent to which EPDS-5 results reflect depression prevalence is unknown. We investigated EPDS-5 ≥7 performance relative to major depression prevalence based on a validated diagnostic interview, the Structured Clinical Interview for DSM (SCID).</p><br />
<p><strong>Methods:</strong><br />
We searched Medline, Medline In-Process & Other Non-Indexed Citations, PsycINFO, and the Web of Science Core Collection through June 2016 for studies with datasets with item response data to calculate EPDS-5 scores and that used the SCID to ascertain depression status. We conducted an individual percentage of EPDS-5 ≥7, pooled SCID major depression prevalence, and the pooled difference in prevalence.</p><br />
<p><strong>Results:</strong><br />
3,958 participants from 19 primary studies were included. Pooled prevalence of SCID major depression was 9.2% (95% confidence interval [CI] 6.0% to 13.7%), pooled percentage of participants with EPDS-5 ≥7 was 16.2% (95% CI 10.7% to 23.8%), and pooled difference was 8.0% (95% CI 2.9% to 13.2%). In the 19 included studies, mean and median ratios of EPDS-5 to SCID prevalence were 2.1 and 1.4 times.</p><br />
<p><strong>Conclusions:</strong><br />
Prevalence estimated based on EPDS-5 ≥7 appears to be substantially higher than the prevalence of major depression. Validated diagnostic interviews should be used to establish prevalence.</p> |
| first_indexed | 2024-03-07T00:38:54Z |
| format | Journal article |
| id | oxford-uuid:825ccf5b-c7f4-41de-8008-7d0a5dea3bbd |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:38:54Z |
| publishDate | 2020 |
| publisher | SAGE Publications |
| record_format | dspace |
| spelling | oxford-uuid:825ccf5b-c7f4-41de-8008-7d0a5dea3bbd2022-03-26T21:36:52ZOverestimation of postpartum depression prevalence based on a 5-item version of the EPDS: Systematic review and individual participant data meta-analysisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:825ccf5b-c7f4-41de-8008-7d0a5dea3bbdEnglishSymplectic ElementsSAGE Publications2020Thombs, BLevis, BLyubenov, AStein, A<p><strong>Objective:</strong><br /> The Maternal Mental Health in Canada, 2018/2019 survey reported that 18% of 7,085 mothers who recently gave birth reported “feelings consistent with postpartum depression” based on scores ≥7 on a 5-item version of the Edinburgh Postpartum Depression Scale (EPDS5). The EPDS-5 was designed as a screening questionnaire, not to classify disorders or estimate prevalence; the extent to which EPDS-5 results reflect depression prevalence is unknown. We investigated EPDS-5 ≥7 performance relative to major depression prevalence based on a validated diagnostic interview, the Structured Clinical Interview for DSM (SCID).</p><br /> <p><strong>Methods:</strong><br /> We searched Medline, Medline In-Process & Other Non-Indexed Citations, PsycINFO, and the Web of Science Core Collection through June 2016 for studies with datasets with item response data to calculate EPDS-5 scores and that used the SCID to ascertain depression status. We conducted an individual percentage of EPDS-5 ≥7, pooled SCID major depression prevalence, and the pooled difference in prevalence.</p><br /> <p><strong>Results:</strong><br /> 3,958 participants from 19 primary studies were included. Pooled prevalence of SCID major depression was 9.2% (95% confidence interval [CI] 6.0% to 13.7%), pooled percentage of participants with EPDS-5 ≥7 was 16.2% (95% CI 10.7% to 23.8%), and pooled difference was 8.0% (95% CI 2.9% to 13.2%). In the 19 included studies, mean and median ratios of EPDS-5 to SCID prevalence were 2.1 and 1.4 times.</p><br /> <p><strong>Conclusions:</strong><br /> Prevalence estimated based on EPDS-5 ≥7 appears to be substantially higher than the prevalence of major depression. Validated diagnostic interviews should be used to establish prevalence.</p> |
| spellingShingle | Thombs, B Levis, B Lyubenov, A Stein, A Overestimation of postpartum depression prevalence based on a 5-item version of the EPDS: Systematic review and individual participant data meta-analysis |
| title | Overestimation of postpartum depression prevalence based on a 5-item version of the EPDS: Systematic review and individual participant data meta-analysis |
| title_full | Overestimation of postpartum depression prevalence based on a 5-item version of the EPDS: Systematic review and individual participant data meta-analysis |
| title_fullStr | Overestimation of postpartum depression prevalence based on a 5-item version of the EPDS: Systematic review and individual participant data meta-analysis |
| title_full_unstemmed | Overestimation of postpartum depression prevalence based on a 5-item version of the EPDS: Systematic review and individual participant data meta-analysis |
| title_short | Overestimation of postpartum depression prevalence based on a 5-item version of the EPDS: Systematic review and individual participant data meta-analysis |
| title_sort | overestimation of postpartum depression prevalence based on a 5 item version of the epds systematic review and individual participant data meta analysis |
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