The role of gelsolin domain 3 in familial amyloidosis (Finnish type)
In the disease familial amyloidosis, Finnish type (FAF), also known as AGel amyloidosis (AGel), the mechanism by which point mutations in the calcium-regulated actin-severing protein gelsolin lead to furin cleavage is not understood in the intact protein. Here, we provide a structural and biochemica...
Main Authors: | Zorgati, H, Larsson, M, Ren, W, Sim, A, Gettemans, J, Grimes, J, Li, W, Robinson, R |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
National Academy of Sciences
2019
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