The role of gelsolin domain 3 in familial amyloidosis (Finnish type)

In the disease familial amyloidosis, Finnish type (FAF), also known as AGel amyloidosis (AGel), the mechanism by which point mutations in the calcium-regulated actin-severing protein gelsolin lead to furin cleavage is not understood in the intact protein. Here, we provide a structural and biochemica...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Zorgati, H, Larsson, M, Ren, W, Sim, A, Gettemans, J, Grimes, J, Li, W, Robinson, R
Fformat: Journal article
Iaith:English
Cyhoeddwyd: National Academy of Sciences 2019

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