Structural and thermodynamic studies on the adenine.guanine mismatch in B-DNA.
The structure of the synthetic dodecamer d(CGCAAATTGGCG) has been shown by single crystal X-ray diffraction methods to be that of a B-DNA helix containing two A(anti).G(syn) base pairs. The refinement, based on data to a resolution of 2.25 A shows that the mismatch base pairs are held together by tw...
| Main Authors: | , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
1990
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